Tag Archives: Sarah R. Moore

 whitlock460Online course brings self-injury to the surface                                                                     Janis Whitlock, Ph.D. ’03, director of the Cornell Research Program on Self-Injury and Recovery (CRPSIR) and a research scientist in the Bronfenbrenner Center for Translational Research, hopes to spotlight the issue by launching a set of web-based                                   education and training courses.
sad girlEarly puberty in girls raises the risk of depression                                                                   Perri Klass interviewed Jane Mendle in her NY Times' column, The Checkup, about Mendle's research with girls who begin puberty earlier than their peers. Read here about her findings and the risks these girls face in adolescence. 
LRDM lab members and 4-H Career Explorations studentsLearning to reduce risky behaviors leads to STEM careers                                                          The Laboratory for Rational Decision Making, led by Dr. Valerie Reyna in Human Development, welcomed 24 high school students from 18 different counties in New York State as part of  the 4-H Career Explorations Conference.
gsalogoGerontological Society selects experts on aging as fellows                     Professors Corinna Loeckenhoff and Elaine Wethington of human development, were two of 94 professionals named on May 31 to the society, which is the largest of its kind seeking to understand aging in the United States.

Students in the News

Sarah MooreHD graduate student in the news: Sarah R. Moore                                                             Sarah R. Moore, Ph.D. student of Dr. Richard A. Depue, was awarded the Early Career Outstanding Paper Award in Developmental Psychology. Read her summary of research on how people differ in their interaction with their environment.
MorenoMarcos Moreno '17 is named a 2016 Udall scholar                                                                  The Udall Scholarship supports undergraduates with excellent academic records and who show potential for careers in environmental public policy, health care and tribal public policy. Moreno is a human development major concentrating in neuroscience in                               the College of Human Ecology.
tumblr_inline_oab7iaDzqM1tqatqb_1280Summer Scholar Spotlight: Deborah Seok ‘17                                                                              In faculty research labs, in communities across the state, and at jobs and internships around the globe, Human Ecology undergrads are making a powerful impact this summer as they apply their knowledge and skills in real-world settings.

 Articles on the Web

Robert SternbergHow can current research inform the development of new methods to assess intelligence?                                                                                                                                    Read the fifth post from the six-part series, "Researching Human Intelligence" on fifteeneightyfour, the blog of Cambridge University Press, with Robert Sternberg,                                           professor of human development.


video play buttonVideo introduces the Program for Research on Youth Development and Engagement (PRYDE), explaining it's mission and introducing key researchers and practitioners involved in the project.                                                                                                                                             
video play button                                                                                                                                                                    Professor Anthony Burrow Discusses Youth and Purpose with Karl Pillemer, Director of BCTR 



Early Career Outstanding Paper Award winner: Sarah R. Moore

A summary of Sarah R. Moore's research, “Neurobehavioral Foundation of Environmental Reactivity.”

By Sarah R. Moore

Sarah Moore, Ph.D. student in Human Development

Sarah R. Moore, Ph.D. student in Human Development

In this review article, I propose a framework for understanding the neurobiological processes that guide how individuals navigate and internalize environments. Previous work brought to attention the empirical evidence that some individuals with particular temperaments, physiological characteristics and, more recently, genetic polymorphisms, demonstrate heightened effects of social environments on development (Belsky & Pluess, 2009). My review article, published in Psychological Bulletin, steps beyond this question of whether individuals vary in responses to social environments, which is now well-established, to why individuals differ in their responses. In other words, I set out to address: What underlies this variation in sensitivity to experience, and how does it develop?

Since the publication of seminal work on gene-environment interactions (Caspi et al., 2002, 2003), gene-environment interaction has become quite common in investigations of individual differences in responsiveness to environmental factors. Collectively, the work suggests that particular genes encoding neurochemicals relate to the degree that social contexts have enduring consequences on developmental outcomes. What was missing in this area was an explanation as to how variation of these neurobiological systems shapes individual differences in the enduring consequences of environmental factors. The first part of my review article thus addresses the neurobiological functions of genes commonly implicated in gene-environment interaction studies of sensitivity. These functions bridge genetic variation affecting neural systems to actual differences in neuroplasticity processes to environmental inputs, explaining mechanistically why particular genotypes might be linked to larger effects of the environment on development.

Inherent to the notion of plasticity is the critical role of experience. Plasticity means that environments are interacting with biology in the development of traits. Despite this accepted view of development as plastic, and thus involving an ongoing interplay of biology and experience, there still exists a heavy emphasis on genetics, in and of itself, wherever one or more genes might be implicated. In the second part of my review, a developmental framework is proposed that accounts for the dynamic nature of the biological processes that are affected by genes. Simply put, if a genetic factor shapes plasticity to the environment, then the history of environmental effects on the biology of the brain is as important to understanding outcomes as the genetic susceptibility factor: Any long-term consequences of such a factor is intrinsically dependent on the surrounding environmental context.

Taken together, the importance of this article lies in its novel insights into the mechanisms that may account for individual variations in sensitivity at a point where the field is in need of such an analysis. For the increasing number of developmentalists turning to research on genetic and biological markers of sensitivity, this article serves to inform the biological role of the prominently studied genes in human development. It also highlights other biological systems relevant to how experiences are registered and internalized. The article advances the current literature's myopic focus on identifying genetic plasticity markers to understanding the plasticity processes at play. The plasticity of neurobiological systems directly accounts for who responds and adapts and to what in the environment. This is essential for understanding developmental change, and for identifying targetable mechanisms of risk. After all, changing genes is not an option.

Ultimately, this article is intended to jumpstart more in-depth research aimed at understanding the nuanced developmental trajectories of individuals with different susceptibilities and unique histories. Understanding how biological tendencies are modified by experience will pave the way for tailored interventions that target the specific needs of individuals and, ultimately, improve psychological and physical health outcomes. I will be continuing this work as a scholar at the Child and Family Research Institute at the University of British Columbia. In this next phase, I will investigate the epigenetic mediators bridging the interplay of genetic variation and experience to neurodevelopment.


Belsky, J., & Pluess, M. (2009). Beyond diathesis stress: Differential susceptibility to environmental influences. Psychological Bulletin, 135 (6), 885–908.

Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297 (5582), 851–854.

Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., et al. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301 (5631), 386–389.